Skin Concerns
· Free-radical defense / antioxidant protection
· Environmental damage
What You’ll See On The Ingredient List
7-dehydrocholesterol
Why Your Skin Needs It
Provitamin D provides antioxidant protection to help defend skin from stressors and free radicals which can leave skin dehydrated and also lead to premature signs of aging. It’s also been known to promote ceramide production, which helps support sustained hydration.
The Clinique Expertise
We’ve added this antioxidant to our formulas to help bolster skin’s natural environmental stress defense system, which can help protect skin against the effects of daily dehydrators like pollution, blue light, and other environmental aggressors. Along with UVA/UVB protection in our SPF products, we help double down on your skin’s defense.
Provitamin D
ingredient to know
Provitamin D
ingredient to know
Provitamin D
Overview
Top Sellers With Provitamin D

Moisture Surge™ Broad Spectrum SPF 28 Sheer Hydrator
Cloud-like cream with SPF 28 hydrates and delivers sheer sun protection.
More Key Ingredients
Aloe Bioferment + HA Complex
Aloe bioferment + HA complex helps hydrate in two ways—attracts moisture and helps retain it.
Alpha Hydroxy Acids
Alpha hydroxy acids gently slough away dead skin cells, revealing smoother and brighter skin.
CL302 Complex
Clinique’s exclusive CL302 Complex helps visibly reduce dark spots and discoloration.
Glycerin
Glycerin supports your skin’s natural moisture barrier by attracting moisture from the air and retaining water in skin to help keep the skin hydrated.
Gyokuro Green Tea
Gyokuro green tea has antioxidant and anti-inflammatory properties that help calm upset skin, reduce irritation, and protect against future damage.
Hyaluronic Acid
Hyaluronic acid plumps skin with hydration, helping it look and feel better instantly.
Lactobacillus Probiotic Ferment
Lactobacillus probiotic ferment helps calm the look of irritation and promotes stronger skin.
Retinoid
Retinoids are derived from vitamin A, which helps accelerate cell turnover and refine skin’s texture.
Safflower Seed
Safflower Seed Oil is rich in linoleic acid and helps leave skin feeling soft and nourished.
Salicylic Acid
Salicylic acid helps clear up clogged pores, blackheads, stubborn acne, and blemishes.
Sigesbeckia Orientalis Extract
Sigesbecia Extract is a powerful procollagen extract, prized for helping skin maintain its natural density.
Performance, Safety, Science
Clinique launched the first-ever line of dermatologist-developed skincare in 1968. The promise: to deliver effective, safe, clinically proven formulas that create great skin. We avoid using allergens, irritants and ingredients in ways that could potentially harm your skin.
Proven results are from how multiple ingredients are combined using the latest scientific breakthroughs to achieve maximum results without irritation. As science evolves, we continuously re-examine ingredients with our researchers, formulators, clinicians, and guiding board-certified dermatologists.
No parabens. No phthalates. No fragrance. Just happy skin.
Frequently Asked Questions: Pro Vitamin D in your routine
Pro Vitamin D provides antioxidant protection to help defend skin from stressors and free radicals which can leave skin dehydrated and also lead to premature signs of aging. It also helps support ceramide production which supports sustained hydration.
By choosing formulas enriched with this ingredient, you’re boosting your skin’s environment-defense system.
Clinique incorporates Pro Vitamin D into select formulas to help bolster skin’s natural environmental stress-defense system and protect skin against daily dehydrators like pollution, blue light, and other environmental aggressors. Using a formula with Pro Vitamin D means you’re aligning with Clinique’s science-driven approach to strong skin resilience.
Here are a few great options:
- Clinique Moisture Surge Broad Spectrum SPF 28 Sheer Hydrator – Cloud-like cream with SPF 28 and includes Pro Vitamin D.
- Clinique Smart Clinical Repair Broad Spectrum SPF 30 Wrinkle Correcting Cream – Anti-aging moisturizer listing Pro Vitamin D in key ingredients.
Treat a Pro Vitamin D-infused product just like you would any high-performance moisturizer or SPF step: cleanse your skin, apply your targeted treatments such as serum or eye treatment, then follow with the product containing Pro Vitamin D as your final step of that sequence morning and evening as directed.
Because Pro Vitamin D works to support environmental defense and hydration, using such a formula in the morning is particularly beneficial when your skin faces daily stressors.
Yes, you can. For example, you might use a serum targeting a specific concern such as uneven tone or fine lines and then apply one of the Clinique products above. Since Pro Vitamin D helps support your skin’s protective and hydrating functions, pairing it with your usual treatment steps makes sense. Follow the lightest-to-heaviest rule, applying serum before moisturizer or SPF, and ensure compatibility if you’re using exfoliants, retinoids, or strong actives.
Yes. Both of the Clinique products recommended above are described as allergy tested and safe for sensitive skin. For example, the Moisture Surge Broad Spectrum SPF 28 Sheer Hydrator is labeled dermatologist tested, safe for sensitive skin, and allergy tested.
No. While Pro Vitamin D supports your skin’s defense against environmental stressors and dehydration, it does not replace primary sun-protection measures in the morning such as a broad-spectrum SPF. If your Clinique product includes SPF, like the Clinique Moisture Surge Broad Spectrum SPF 28 Sheer Hydrator or Clinique Smart Clinical Repair Broad Spectrum SPF 30 Wrinkle Correcting Cream, it serves dual purposes of protection and moisture. If you use a formula without SPF, you still need to apply a dedicated sunscreen after.
Because Pro Vitamin D works on your skin’s protective and moisture-retention systems rather than quick surface changes, you can expect gradual improvement in how resilient and hydrated your skin looks and feels. Track your skin’s comfort, plumpness, and ability to resist environmental stress over two to four weeks and beyond.